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D3h2ln-at2 human invasive breast cancer cell line expressing the human angiotensin ii-receptor at2

D3H2LN-AT2 cell line stably expressing firefly luciferase, GFP and Flagged human AT2 receptor.rnEmpty vector infected cell line is also available.

Interest / Relevance: Metastatic breast cancer cell line model to study the role of human Angiotensin II AT2 receptor in breast cancer. rnThis cell line can be used for the screening of selective AT2 receptor ligands.rnThis cell line is suitable for in vitro and in vivo analyses of tumor growth and metastasis by fluorescence and bioluminescence.rnTumor growth and metastasis in nude mice

Keywords: Breast cancer , Tumor growth , Metastasis , AT2 signalling , Bioluminescence

Scientist's name: Clara NAHMIAS
Sylvie RODRIGUES-FERREIRA

Publications:

A novel cellular model to study angiotensin II AT2 receptor function in breast cancer cells.2012. Rodrigues-Ferreira S. Morel M. Reis R.I. Cormier F. Baud V. Costa-Neto C.M. Nahmias C. Int. J. Peptides in press

Reference:

RT00457

Type of research tool: Cell Lines

Therapy area(1): Oncology

Therapy area(2): Others

Uses(1): Academic Research

Uses(2): Industry Research (screening, tox.studies, bioreactor, ...)

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Organism: Human

Tissue: Breast, adenocarcinoma metastatic

Passage Number: From passage 10

Subculture Routine: Passage 1/10 twice a week

Culture Medium: DMEM 4.5g/L glucose Glutamax supplemented with 10% SVF, 1%penicillin/streptomycin

Growth Properties: Adherent

Rare disease: No

Last update: 08/07/2024

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