Ug5ln cell line

UG5LN were generated by transfection of osteocarcinoma cancer U20S cells with the (GAL4RE)5-betaGlobin-Luciferase-SV40-Neomycin plasmid. The plasmid (GAL4RE)5-betaGlob-Luc-SVNeo contains a luciferase gene driven by a pentamer of yeast activator GAL4 binding sites in front of beta-globin promoter and a neomycin phosphotransferase gene under the control of SV40 promoter.

Interest / Relevance: These cells are a negative control cell line for measurement of nuclear receptor activity.
Keywords: luciferase, pharmaceutical and environmental chemicals
Scientist's name: Patrick BALAGUER

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