Back to results

Rat mesothelial cell line f3-1

Transformed rat mesothelial cell line isolated from the peritoneal fluid of a female rat (Fischer F344) after 356 days of induction with crocidolite (blue asbestos) injected intraperitoneously.

Interest / Relevance: - Academic Research: identification of markers of neoplastic / transformed mesothelial cells, analyses of chromosomal damage induced by asbestos, studies of the mechanism of asbestos-induced oncogenesis, implication of fibrosis and inflammation.
- Industry research: antibody production, screening of new anticancer agents, identification of factors that increase mesothelial proliferation and migration.
- Therapeutic: development of epigenetic drugs, design of cancer vaccines, regenerative medicine applications.

Cellular and Molecular Biology, Immunology.

Scientist's name: Daniel POULIQUEN

Reference:

RT00415

Type of research tool: Cell Lines

Therapy area(1): Oncology

Therapy area(2): Immunology

Therapy area(3): Others

Therapy area(4): Infectious Diseases

Uses(1): Academic Research

Uses(2): Proof of concept in vitro

Uses(3): Industry Research (screening, tox.studies, bioreactor, ...)

Uses(4): Diagnostic

Uses(5): Therapeutic

Inserm Transfert
Research Tools

E-mail

Organism: Rat

Tissue: Mesothelium (peritoneal cavity)

Morphology: Epithelioid

Passage Number: 4

Culture Medium: RPMI 1640 supplemented with 10% FCS and 2mM L-Glutamine

Growth Properties: In 6-well plates (300,000 cells/well): Doubling time: 24-48h. Saturation density >200,000 cells / sq-cm.

Karyotype: under investigation

Rare disease: No

Last update: 11/09/2024

You might also be interested in

RT00399

Uses: Industry Research (screening, tox.studies, bioreactor, ...)

Therapy Area: Others

Type of research tool: Laboratory Animals

Transgenic mouse model for myotonic dystrophy:

This transgenic mice model contains large human genomic DNA sequence carrying the DMPK gene with […]

Read more

RT00344

Uses: Industry Research (screening, tox.studies, bioreactor, ...)

Therapy Area: Metabolic Disorders

Type of research tool: Antibodies

Rat anti-mouse cd26 (mouse dipeptidyl peptidase

Rat monoclonal antibody recognizing the cell surface antigen DPP IV (CD26) involved in T cell […]

Read more

RT00480

Uses: Therapeutic

Type of research tool: Laboratory Animals

Gfp-tagged mucin-reporter mouse model

To follow the Muc5b gel-forming mucin production, we tagged with a GFP variant the corresponding […]

Read more

RT00394

Uses: Diagnostic

Therapy Area: Others

Type of research tool: Cell Lines

Rbl-2h3 rat mast cell line : in vitro

Rat mast cell line (RBL-2H3) transfected with the cDNAs encoding the three subunits (alpha, beta, […]

Read more

RT00286

Uses: Industry Research (screening, tox.studies, bioreactor, ...)

Therapy Area: Others

Type of research tool: Antibodies

Mouse anti-histone h1zero (clone 27e8e10)

Read more

RT00287

Uses: Industry Research (screening, tox.studies, bioreactor, ...)

Therapy Area: Others

Type of research tool: Antibodies

Mouse anti-histone h1zero (clone 34b10h4)

Read more

RT00320

Uses: Industry Research (screening, tox.studies, bioreactor, ...)

Therapy Area: Oncology

Type of research tool: Antibodies

Mouse anti mouse ccl5 monoclonal antibody (clone

Mouse monoclonal antibody directed against mouse CCL5.
Antibody was produced by immunising CCL5 […]

Read more

RT00469

Uses: Proof of concept in vitro

Therapy Area: Others

Type of research tool: Antibodies

Human ferroportin polyclonal antibodies

Rabbit Polyclonal antibodies raised against 3 differents portions of the iron exporter Human […]

Read more

RT00488

Uses: Industry Research (screening, tox.studies, bioreactor, ...)

Therapy Area: Genito Urinary System

Type of research tool: Know How

Technique to isolate live renal proximal tubular

We isolate renal proximal tubular cells using the proximal tubular marker Prominin-1.
We use a […]

Read more

RT00486

Uses: Industry Research (screening, tox.studies, bioreactor, ...)

Therapy Area: Genito Urinary System

Type of research tool: Cell Lines

Primary cultures of mice proximal tubular cells

Proximal tubular cells are isolated by magnetic sorting coupled with microbeads-conjugated […]

Read more

RT00559

Uses: Industry Research (screening, tox.studies, bioreactor, ...)

Therapy Area: Oncology

Type of research tool: Cell Lines

Hg5ln gal4-hppar gamma cell line

HG5LN were generated by transfection of cervical cancer HeLa cells with the […]

Read more

RT00005

Uses: Therapeutic

Type of research tool: Cell Lines

Cpt1 expressing yeast strains

Saccharomyces cerevisiae expressing under the GAL promoter either the wild-type rat liver CPT1, […]

Read more