D3h2ln-at2 human invasive breast cancer cell line expressing the human angiotensin ii-receptor at2

D3H2LN-AT2 cell line stably expressing firefly luciferase, GFP and Flagged human AT2 receptor.
Empty vector infected cell line is also available.

Interest / Relevance: Metastatic breast cancer cell line model to study the role of human Angiotensin II AT2 receptor in breast cancer.
This cell line can be used for the screening of selective AT2 receptor ligands.
This cell line is suitable for in vitro and in vivo analyses of tumor growth and metastasis by fluorescence and bioluminescence.
Tumor growth and metastasis in nude mice

Keywords: Breast cancer , Tumor growth , Metastasis , AT2 signalling , Bioluminescence

Scientist's name: Clara NAHMIAS
Sylvie RODRIGUES-FERREIRA

Publications:

A novel cellular model to study angiotensin II AT2 receptor function in breast cancer cells.2012. Rodrigues-Ferreira S., Morel M., Reis R.I., Cormier F., Baud V., Costa-Neto C.M., Nahmias C. Int. J. Peptides, in press

Reference:

RT00457

Type of research tool: Cell Lines

Therapy area(1): Oncology

Therapy area(2): Others

Uses(1): Academic Research

Uses(2): Industry Research (screening, tox.studies, bioreactor, ...)

Inserm Transfert
Research Tools

E-mail

Organism: Human

Tissue: Breast, adenocarcinoma metastatic

Passage Number: From passage 10

Subculture Routine: Passage 1/10 twice a week

Culture Medium: DMEM 4.5g/L glucose Glutamax supplemented with 10% SVF, 1%penicillin/streptomycin

Growth Properties: Adherent

Rare disease: No

Last update: 11/09/2024

D3h2ln-at2 human invasive breast cancer cell line expressing the human angiotensin ii-receptor at2

You might also be interested in

Transgenic mouse model for myotonic dystrophy:

Rat anti-mouse cd26 (mouse dipeptidyl peptidase

Gfp-tagged mucin-reporter mouse model

Rbl-2h3 rat mast cell line : in vitro

Mouse anti-histone h1zero (clone 27e8e10)

Mouse anti-histone h1zero (clone 34b10h4)

Mouse anti mouse ccl5 monoclonal antibody (clone

Human ferroportin polyclonal antibodies

Technique to isolate live renal proximal tubular

Primary cultures of mice proximal tubular cells

Hg5ln gal4-hppar gamma cell line

Cpt1 expressing yeast strains