147

therapeutic
published patents

56

oncology
published patents

310

research tools

46

diagnostic
published patents

Our Technology Offers

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You want access to an innovative offer which is based on the excellence of Inserm, the leading academic research and clinical institute dedicated to human health in Europe? Find out our technologies offers of patents and research tools: here is a sample of our patents.

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Mouse t lymphoma cell line – ko99l

The murine primary KO99L cell line was established by cultivating tumoral thymocytes from a tPTEN-/- mouse. Mice carrying a T cell-specific deletion […]

Mouse t lymphoma cell line expressing luciferase – ko99l/luc

The primary KO99L cell line was established by cultivating tumoral thymocytes from a tPTEN-/- mouse. KO99L cells were transduced with a […]

A breast-cancer cell line expressing a bret biosensor to monitor pi-3

We have developed a MCF7-derived cell line stably co-expressing the pleckstrin homology (PH) domain of Akt fused to Renilla luciferase (Luc-Akt-PH) […]

Transgenic mouse model for myotonic dystrophy: dmsxl carrying

This transgenic mice model contains large human genomic DNA sequence carrying the DMPK gene with very large repeat (>1200 CTG). They show […]

Technique to isolate live renal proximal tubular cells from any mouse

We isolate renal proximal tubular cells using the proximal tubular marker Prominin-1.We use a 4°C, enzyme free protocole allowing high quality […]

Cpt1 expressing yeast strains

Saccharomyces cerevisiae expressing under the GAL promoter either the wild-type rat liver CPT1, mutated rat liver CPT1 or chimeric CPT. CPT1A activity […]

High-throughput screening for small psycho-active molecules in

Here, we describe a simple, behaviour-based approach to identify in vivo novel psycho-active molecules in zebrafish embryos. Using an automated […]

Labeled mouse escherichia coli (gfp or dsred)

An E. coli was isolated from the mouse feces and transformed with a plasmid expressing either the GFP or the DSRed under an E coli specific promoter. […]

Prkcdg510s/g510s mice – preclinical model of lupus

We introduced the Prkcd G510S mutation that we previously associated to a Mendelian cause of SLE in the mouse genome, by means of CRISPR-Cas9 gene […]

Xenograft models to study stem and chemoresistant cells, and to assess

We have recently contributed to establish a robust xenotransplantation model (NSG, NRG) to study the leukemic engraftment as well as the stem cell […]

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