The murine primary KO99L cell line was established by cultivating tumoral thymocytes from a tPTEN-/- mouse. Mice carrying a T cell-specific deletion […]

The primary KO99L cell line was established by cultivating tumoral thymocytes from a tPTEN-/- mouse. KO99L cells were transduced with a […]

Saccharomyces cerevisiae expressing under the GAL promoter either the wild-type rat liver CPT1, mutated rat liver CPT1 or chimeric CPT. CPT1A activity […]

This transgenic mice model ("DMSXL") contains large human genomic DNA sequence carrying the DMPK gene with very large repeat (>1200 CTG). […]

Transgenic mouse model carrying the myotonic dystrophy type 1 (DM1) locus (45kb of human sequences) with the DMPK gene and about 300 unstable CTG […]

We can provide mice a nutritional model of mice which become either type 2 diabetic without obesity, or obese and diabetic or mainly obese. […]

The class B, type I scavenger receptor (Srb1 or Scarb1) is a cell surface HDL receptor. It plays a key role in determining the levels of plasma […]

We introduced the Prkcd G510S mutation that we previously associated to a Mendelian cause of SLE in the mouse genome, by means of CRISPR-Cas9 gene […]

Amyloidosis is a rare disease caused by extracellular deposition of insoluble abnormal fibrils derived from aggregation of a misfolded variant of a […]

100% of the animals spontaneously tumor in the distal part of the colon after 7 month of age, or within 5 weeks after bone marrow transfer. The […]