Profiling blood lymphocytes reactivity against cancer cells

In vitro trogocytosis of PKH67-stained cancer cells as a measure of their interactions with bulks of PBMC from patients. This profiling give the quantification of specific interactions of different subsets from PBMC with different cancer cells.

Interest / Relevance: This profiling provides interaction signatures for the immunomonitoring of cancers in case of cancer patients for example to adress the level of their immune system reactivity at diagnostic and/or during therapeutic treatment.
Keywords: immune reactivity , trogocytosis , immunomonitoring , interactions
Scientist's name: Mary POUPOT
Jean-Jacques Fournié, Frédéric Pont

Reference:

RT00436

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Mary POUPOT
Inserm Transfert
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Accessible for: Fee-for-service research, Collaboration, Training / Know-How License
Equipment available: This method require a flow cytometer with at least two lasers and at best three lasers.
Last update: 05/12/2019

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