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therapeuticpublished patents
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TSSP is a novel protease suspected to edit the peptide repertoire presented by MHC class II molecules in the thymus. Prss16, the gene coding for TSSP […]
This transgenic mice model ("DMSXL") contains large human genomic DNA sequence carrying the DMPK gene with very large repeat (>1200 CTG). […]
Transgenic mouse model carrying the myotonic dystrophy type 1 (DM1) locus (45kb of human sequences) with the DMPK gene and about 300 unstable CTG […]
Uncoupling protein (UCP) 3 is a mitochondrial inner membrane protein expressed predominantly in glycolytic skeletal muscles.Transgenic mice were […]
This mouse is deficient for TP53INP1 (both isoforms TP53INP1alpha and TP53INP1beta). TP53INP1 is a key stress factor endowed with a tumor suppressor […]
mouse exhibiting a Lox-APL transgene leading to a tissue specific invalidation. […]
We can provide mice a nutritional model of mice which become either type 2 diabetic without obesity, or obese and diabetic or mainly obese. […]
The class B, type I scavenger receptor (Srb1 or Scarb1) is a cell surface HDL receptor. It plays a key role in determining the levels of plasma […]
We introduced the Prkcd G510S mutation that we previously associated to a Mendelian cause of SLE in the mouse genome, by means of CRISPR-Cas9 gene […]
To follow a gel-forming mucin production, we tagged with a GFP variant a mouse mucin gene. This reporter mouse allow also to follow goblet cell number […]
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UALH were generated by transfection of osteocarcinoma cancer U2OS cells with the […]
Rat mast cell line (RBL-2H3) transfected with the cDNAs encoding the three subunits (alpha, beta, […]
This stable clone of HEK 293 cells has stably incorporated the sequence encoding the long isoform of […]
HG5LN were generated by transfection of cervical cancer HeLa cells with the […]
HT29MTX10-6, HT29MTX10-5 and HT29MTX10-4 cell populations were isolated from the colon cancer cell […]
Hek293T cells were transfected with short form human leptin receptors (OBR) tagged individually with […]
Ba/F3 cells are mouse pro-B lymphocytes that are dependent on IL-3 for survival/growth. We stably […]
Transformed rat mesothelial cell line (= myofibroblast) isolated from the peritoneal fibrosis […]
Transformed rat mesothelial cell line isolated from the peritoneal fluid of a female rat (Fischer […]
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