147

therapeutic
published patents

56

oncology
published patents

310

research tools

46

diagnostic
published patents

Our Technology Offers

Welcome to our Technology Offers website

You want access to an innovative offer which is based on the excellence of Inserm, the leading academic research and clinical institute dedicated to human health in Europe? Find out our technologies offers of patents and research tools: here is a sample of our patents.

Mouse model for multiple sclerosis mediated by cd8 t cells

we generated mice in which the model antigen influenza hemagglutinin (HA) is selectively expressed as a neo-self antigen in oligodendrocytes, referred […]

Microbiota dependent spontaneous colorectal cancer

100% of the animals spontaneously tumor in the distal part of the colon after 7 month of age, or within 5 weeks after bone marrow transfer. The […]

Transgenic mice model for myotonic dystrophy type 1 (dm1) dmsxl

This transgenic mice model ("DMSXL") contains large human genomic DNA sequence carrying the DMPK gene with very large repeat (>1200 CTG). […]

Conditional tpm3-alk transgenic mice

TPM3-ALK (Tropomyosin 3-Anaplastic lymphoma kinase) is oncogenic tyrosine kinase implicated in the pathogenesis of human ALK-positive lymphoma. We […]

Apoa2 humanized transgenic mouse – line delta

The mice are hemizygous for the human apolipoprotein A2 (ApoA2) gene expressed under the control of the homologous promoter (-911/+2045). They are […]

Apoa2 humanized transgenic mouse – line beta

The mice are hemizygous for the human apolipoprotein A2 (ApoA2) gene expressed under the control of the homologous promoter (-911/+2045). They are […]

Apoa2 humanized transgenic mouse – line lambda

The mice are hemizygous for the human apolipoprotein A2 (ApoA2) gene expressed under the control of the homologous promoter (-911/+2045). They are […]

Mouse models of amyloidosis

Amyloidosis is a rare disease caused by extracellular deposition of insoluble abnormal fibrils derived from aggregation of a misfolded variant of a […]

Mucin-reporter

To follow a gel-forming mucin production, we tagged with a GFP variant a mouse mucin gene. This reporter mouse allow also to follow goblet cell number […]

Tssp-deficient mice, a model to identify new essential diabetogenic

TSSP is a novel protease suspected to edit the peptide repertoire presented by MHC class II molecules in the thymus. Prss16, the gene coding for TSSP […]

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