Real time no measurement

Real time constant amperometric detection of NO in tissues/cells.

This gaseous neurotransmitter has a very short half-life (*5 s) and is usually studied by using indirect detection.
We set up an original method to measure in real-time conditions hypothalamic nitric oxide production after intragastric glucose administration.

Keywords: NO , ROS
Scientist's name: Philippe VALET
Claude KNAUF
Publications:
T. DUPARC, D. NASLAIN, A. COLOM, G.G. MUCCIOLI, N. MASSALY, N.M. DELZENNE, P. VALET, P.D. CANI, C. KNAUF. Jejunum inflammation in obese and diabetic mice impairs enteric glucose detection and modifies nitric oxide release in the hypothalamus. Antiox. Red. Signal. 14: 415-23, 2011.

T. DUPARC, A. COLOM, P.D. CANI, N. MASSALY, S. RASTRELLI, A. DROUGARD, S. LE GONIDEC, L. MOULÉDOUS, B. FRANCES, I. LECLERCQ, C. LLORENS-CORTES, J.A. POSPISILIK, N.M. DELZENNE, P. VALET, I. CASTAN-LAURELL & C. KNAUF. Central apelin controls glucose homeostasis via a nitric oxide dependent pathway in mice. Antiox. Red. Signal. 2011.

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