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Mouse anti-human/mouse/rat tspan5 (clones ts5-2 and ts5-3)

This mAb recognizes Tspan5, a member of the Tetraspanin superfamily. It recognizes the human, mouse and rat proteins which are 100% identical. First Tspan5 mAb ever produced.

Interest / Relevance: Tspan5 is a new regulator of Notch signaling through an action on the protease ADAM10.

Keywords: Tetraspanin, ADAM10, Notch

Scientist's name: Eric RUBINSTEIN
Martine BILLARD Stephanie CHARRIN

Reference:

RT00510

Type of research tool: Antibodies

Therapy area(1): Central Nervous System

Therapy area(2): Oncology

Uses(1): Academic Research

Type of Product: Monoclonal Antibody

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Clones available: TS5-2, TS5-3

Isotype: lgG2a

Source: Mouse

human, mouse, rat

Specificity: human, mouse, rat

Immunogen Seq ID: Tspan5 KO mice (C57/B6) were immunized with U2OS cells transfected with Tspan5-GFP, Final boost with a Tspan5 immunoprecipitate

Cellular Distribution: large, higher expression in the brain and the ovary

Rare disease:

Last update: 25/11/2022

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