Microbiota dependent spontaneous colorectal cancer

100% of the animals spontaneously tumor in the distal part of the colon after 7 month of age, or within 5 weeks after bone marrow transfer. The mutation affect the immune system and not the stromal cells. Tumor development is totally prevented in the absence of microbiota.

Interest / Relevance: Analysis of cancer treatment.
Analysis of microbiota effects on cancer.
Analysis of metabolism effetcs on cancer.
Keywords: microbiota , Colorectal cancer



Business Developper
Julien MARIE
Inserm Transfert
Research Tools
Species: Mus musculus
Genotype: Mutation within the immune system
Genetic Background: C57BL/6
Rare disease:
Last update: 19/05/2023

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