The present invention relates to polypeptide for engineering integrase chimeric proteins and their use in gene therapy. A key challenge for gene […]
The present invention relates to nuclease protein fusions for enhancing genome editing by homology-directed transgene integration (HDI).The inventors […]
This invention results from Pharmacologically Active Microcarriers (PAM) which are based on a biocompatible and biodegradable material. These […]
The present invention relates to the treatment of autoimmune diseases. The inventors determined that the cathelicidin related antimicrobial peptide […]
The present invention relates to the treatment of IgE-mediated disease. The inventors hypothesized that formation of immune complexes between […]
The present invention relates to N-(3-(5-(pyrimidin-4-yl)thiazol-4-yl)phenylsulfonamide compounds which are useful as inhibitors of protein kinases, […]
Several gastrointestinal and gynecological malignancies have the potential to disseminate and grow in the peritoneal cavity. The occurrence of […]
Immunoglobulins (Ig) are expressed either on the surface of B cells or as secreted antibodies by plasma cells that represents the final stage of B […]
The present invention relates to the treatment of acidosis related diseases. In this study, the inventors have investigated how human monocytes adapt, […]
The Inventors developed conditions allowing to efficiently detect differences in cardiomyocytes relaxation phases associated with increased […]