Apelin analogs for the treatment of heart failure

The invention related to metabolically stable Apelin analogs and their use for the prevention or the treatment of diseases mediated by the apelin […]

Novel target candidate for the prevention and treatment of respiratory

The present invention relates to methods and pharmaceutical compositions for the prevention and treatment of respiratory bacterial infections and more […]

Ppar-gamma agonist as target for the treatment of rapidly progressive

This study demonstrates the pivotal role of the local PPAR-gamma agonist system in maintaining podocyte quiescence and orchestrating the global […]

Anti notch3 antibody for cadasil treatment

The present invention relates to an anti-Notch 3 antibody therapy useful for treatment of patients with cerebral autosomal dominant arteriopathy with […]

Lipid antisens oligonucleotide targeting fxyd2 as a therapeutic agent

The present invention relates to an inhibitor of FXYD2 gene expression for use in a method for treating neuropathic pain in a patient in need thereof. […]

Soluble apps?-based gene therapy in alzheimer’s disease

The present invention relates to a method of treating Alzheimer’s disease by administration to the subject of a therapeutically effective amount of […]

Anti-kit mab for the treatment of cancer (aml, gist)

The invention relates to two isolated human neutralizing antibodies that binds to an undisclosed Tyrosine Kinase Receptor, which further induces […]

Neuroglobin gene therapy for use in the treatment or prevention of a

Mitochondrial dysfunction is responsible for hereditary optic neuropathies. We wished to determine whether preserving mitochondrial […]

Antibody protecting from bscb leakage induced cns damages

The present invention relates to an anti-NMDA antibody or fragment or derivative thereof which is effective in inhibiting the deleterious effects of […]

M-csf for preventing or treating myeloid cytopenia and related

The invention relates to a method for preventing or treating myeloid cytopenia and related complications such as infections in patients undergoing […]