Ptgdrs, cxcr4 and basophils in systemic lupus erythematosus

The present invention relates to PTGDRs, CXCR4 and Basophils to treat in Systemic Lupus Erythematosus. In particular, the present invention concerns a PTGDR-1 antagonist, a PTGDR-2 antagonist, a dual PTGDR-1/PTGDR-1 antagonist, or a combination of PTGDR-1 antagonist and PTGDR-2 antagonist, and pharmaceutical compositions containing them, for use for preventing and/or treating SLE.

Keywords: Lupus, PTGDRs, CXCR4
Patent Application number: EP15 305 222.0
Inventors:
Christophe PELLEFIGUESNicolas CHARLES
Publications:
Nat Commun. 2018 Feb 20;9(1):725. doi: 10.1038/s41467-018-03129-8.

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