Apelin analogs for the treatment of Heart Failure

The invention related to metabolically stable Apelin analogs and their use for the prevention or the treatment of diseases mediated by the apelin receptor in particular of cardiovascular disease (heart failure, hypertension, pulmonary hypertension, kidney failure) and inappropriate vasopressin secretions (SIADH). FASEB J. 2017 Feb;31(2):687-700. 4.

Keywords : Hypertension, Pulmonary Hypertension, Apelin, Syndrome of inappropriate antidiuretic hormone secretion
Patent Application number : EP14307170.2
Patent Application date : 2014-12-23
Multidisciplinary field : -
Technology/Engineering : -
Technological Platform : -
Rare disease : -
Second indication : -
Inventors : Dominique BONNET
Publications :
  • FASEB J. 2017 Feb;31(2):687-700. doi: 10.1096/fj.201600784R. Epub 2016 Nov 4.

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