Labeled mouse escherichia coli (gfp or dsred)

An E. coli was isolated from the mouse feces and transformed with a plasmid expressing either the GFP or the DSRed under an E coli specific promoter. this bacteria can be followed into the body and DSRed labelled bacteria can be sorted by FACS analysis

	Clinical Annotation	Pathology Report	Informed consent	Available for Contract research	Available for Material transfer
Tissue	Yes	Yes	Yes	Yes	Yes
Serum	Yes	Yes	Yes	Yes	Yes
Plasma	Yes	Yes	Yes	Yes	Yes
DNA	Yes	Yes	Yes	Yes	Yes
RNA	Yes	Yes	Yes	Yes	Yes
Proteins	Yes	Yes	Yes	Yes	Yes

Additional information on samples: Contact us for more information

Interest / Relevance: These bacteria are useful to study in vivo and in in vitro intestinal permeability, in vivo and in vitro phagocytosis, immune system activation

Keywords: Bacterial translocation , Intestinal permeability , Inflammation , Phagocytosis , Biomarkers

Scientist's name: Rémy BURCELIN

Publications:

Intestinal mucosal adherence and translocation of commensal bacteria at the early onset of type 2 diabetes: molecular mechanisms and probiotic treatment.

Amar J, Chabo C, Waget A, Klopp P, Vachoux C, Bermúdez-Humarán LG, Smirnova N, Bergé M, Sulpice T, Lahtinen S, Ouwehand A, Langella P, Rautonen N, Sansonetti PJ, Burcelin R.

EMBO Mol Med. 2011 Sep;3(9):559-72

Reference:

RT00463