147

therapeutic
published patents

56

oncology
published patents

310

research tools

46

diagnostic
published patents

Our Technology Offers

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You want access to an innovative offer which is based on the excellence of Inserm, the leading academic research and clinical institute dedicated to human health in Europe? Find out our technologies offers of patents and research tools: here is a sample of our patents.

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Selective antiestrogen binding site (aebs) ligands in the diphenyl

We can offer and produce selective AEBS lignads for research purpose only.rnThese compounds are potent inducers of breast cancer cell differentiation […]

Establishment of redifferentiated cells after treatment of neoplastic

When undifferentiated, invasive neoplastic cell lines are treated with an optimal time / concentration combination of curcumin (under conditions […]

Labeled mouse escherichia coli (gfp or dsred)

An E. coli was isolated from the mouse feces and transformed with a plasmid expressing either the GFP or the DSRed under an E coli specific promoter. […]

Staining of human tissues for multi-color confocal microscopy analysis

This proposition describes a technique that allowed us to successfully stain human tissues with fluorochrome labelled antibodies for confocal and […]

Profiling blood lymphocytes reactivity against cancer cells

In vitro trogocytosis of PKH67-stained cancer cells as a measure of their interactions with bulks of PBMC from patients. This profiling give the […]

Three-dimensional multicellular spheroid cultures

When culture in suspension many mammalian cell types can aggregate into 3D-spheroids. These multicellular cultures mimic real tissues or tumours and […]

Real time no measurement

Real time constant amperometric detection of NO in tissues/cells.rnrnThis gaseous neurotransmitter has a very short half-life (*5 s) and is usually […]

Screening and characterization of new histone deacetylase inhibitors

Using BRET technology, we designed a method to measure histone acetylation in living cells. Cells are transfected with a vector coding for a […]

Animal models of fibrosis

UUO: This model is induced in mice or rats by unilateral ureteral ligation (UUO) of the left ureter. The animals rapidly develop, within a few days, […]

Technique to isolate live renal proximal tubular cells from any mouse

We isolate renal proximal tubular cells using the proximal tubular marker Prominin-1.rnWe use a 4°C, enzyme free protocole allowing high quality […]

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