147

therapeutic
published patents

56

oncology
published patents

310

research tools

46

diagnostic
published patents

Our Technology Offers

Welcome to our Technology Offers website

You want access to an innovative offer which is based on the excellence of Inserm, the leading academic research and clinical institute dedicated to human health in Europe? Find out our technologies offers of patents and research tools: here is a sample of our patents.

Mouse anti-human fli-1 (friend leukemia virus integration 1) (clone

Targets : Human FLI-1 and EWS-FLI-1. Applications : Western-blot, Immunoprecipitation, intracellular immunofluorescence […]

Mouse anti-human/mouse/rat tspan5 (clones ts5-2 and ts5-3)

This mAb recognizes Tspan5, a member of the Tetraspanin superfamily. It recognizes the human, mouse and rat proteins which are 100% identical. First […]

Microbiota dependent spontaneous colorectal cancer

100% of the animals spontaneously tumor in the distal part of the colon after 7 month of age, or within 5 weeks after bone marrow transfer. The […]

Conditional bioluminescent tmp3-alk cell line

Overexpression and activation of TMP3-ALK tyrosine kinase fusion protein is a causal oncogenic event in the development of Anaplastic Large Cell […]

Conditional tpm3-alk transgenic mice

TPM3-ALK (Tropomyosin 3-Anaplastic lymphoma kinase) is oncogenic tyrosine kinase implicated in the pathogenesis of human ALK-positive lymphoma. We […]

Ex vivo culture system for screening compounds targeting

A novel, ex vivo niche-based hypoxic culture system for maintaining Leukaemia Initiating Cells (LICs) from patients and an associated method to […]

Xenograft models to study stem and chemoresistant cells, and to assess

We have recently contributed to establish a robust xenotransplantation model (NSG, NRG) to study the leukemic engraftment as well as the stem cell […]

D3h2ln-at2 human invasive breast cancer cell line expressing the human

D3H2LN-AT2 cell line stably expressing firefly luciferase, GFP and Flagged human AT2 receptor. Empty vector infected cell line is also available. […]

Screening and characterization of new histone deacetylase inhibitors

Using BRET technology, we designed a method to measure histone acetylation in living cells. Cells are transfected with a vector coding for a […]

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