Familial adenomatous polyposis (FAP) patients harbor mutations in the APC gene and will develop adenoma and early colorectal cancer. Taking biopsies […]

Dose-limiting toxicity poses a major limitation to the clinical utility of targeted cancer therapies, often arising from target engagement in […]

The spleen clears rigid erythrocytes from the circulation. Drug-induced stiffening of Plasmodium falciparum intra-erythrocytic sexual stages (mature […]

The present invention relates to a method for promoting wound healing in a subject suffering from Ectodermal dysplasia in need thereof comprising a […]

The present invention relates to the treatment of idiopathic pulmonary fibrosis. Today, there is no cure for IPF. The inventors showed that EPAC1 […]

Inventors have surprisingly found that Emricasan is a much more potent inhibitor of monocyte differentiation compared to q-VD-OH by its ability to […]

The present invention relates to the treatment of acidosis related diseases. In this study, the inventors have investigated how human monocytes adapt, […]

The present invention relates to PTGDRs, CXCR4 and Basophils to treat in Systemic Lupus Erythematosus. In particular, the present invention concerns a […]

The present invention relates to N-(3-(5-(pyrimidin-4-yl)thiazol-4-yl)phenylsulfonamide compounds which are useful as inhibitors of protein kinases, […]

The present invention relates to methods for enhancing the potency of the immune checkpoint inhibitors. In particular, the present invention relates […]