Osteoarthritis (OA) is a type of degenerative joint disease that results from breakdown of joint cartilage and underlying bone. Here, the inventors […]

The invention relates to an engineered glomerular endothelial cell comprising areduction in expression of a human leukocyte antigen and its use in an […]

Engraftment of hematopoietic stems cells (HSCs) is a potentially life-saving treatment therapy for various conditions including genetic blood cell […]

Multiple sclerosis (MS) is a neuroinflammatory disease driven by B- and T-cells. The role of follicular regulatory T cells (Tfr) in MS remains […]

The inventors developed a multiplex test for the detection of autoantibodies directed against five DEJ proteins (NC16A and C-terminal domain of BP180, […]

The present invention relates to methods of determining the clinical phenotype of patients suffering from hidradenitis suppurativa (HS), a chronic […]

Allogeneic kidney transplantation is a common transplant procedure and an optimal form of therapy for individuals who reach end-stage renal disease, […]

Using NLRP3-deficient U937 cells reconstituted with doxycycline-inducible NLRP3 variants in response to NLRP3 induction, the present inventors have […]

Systemic lupus erythematosus (SLE) is an autoimmune disease in which circulating immune complexes can cause different types of glomerulonephritis, […]

CD4+ Foxp3- conventional T cells (Tconv) play a key role in the inflammatory process involved in rheumatoid arthritis (RA). It is now becoming […]