published patents


published patents


research tools


published patents

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You want access to an innovative offer which is based on the excellence of Inserm, the leading academic research and clinical institute dedicated to human health in Europe? Find out our technologies offers of patents and research tools: here is a sample of our patents.

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Nanoparticles for treating or preventing a cardiomyopathy and

Anthracyclines such as doxorubicin are chemotherapeutic molecules are also widely incorporated in many chemotherapy protocols. However, their clinical […]

Use of mast cell stabilizer for the treatment of heart failure with

Heart failure with preserved ejection fraction (HFpEF) which results from diastolic dysfunction is a growing epidemiologic problem. However, the […]

Use of inhibitors of phosphatase activity of soluble epoxide for the

The growing prevalence of obesity and type 2 diabetes complicates risk and clinical management by potentiating and/or exacerbating hypertension, […]

Use of pi3kc2¿ inhibitors for the preservation of vascular

Ischemic conditions are a leading cause of death for both men and women. Ischemia, a condition characterized by reduced blood flow and oxygen to an […]

A b cell depleting agent for the treatment of atherosclerosis or post

New anti-atherogenic strategies based on B cell modulation, and suggest that patients currently treated with CD20 antibodies for other immune-mediated […]

Gdf3 as biomarker and biotarget in post-ischemic cardiac remodeling

Markers of an intense scarring process in the early phase post- myocardial infarction (MI) are still undetermined, and the identification of patients […]

Methods for predicting and treating cardiac dysfunction

Ageing myocardium undergoes structural and functional changes characterized by progressive cardiomyocyte hypertrophy, interstitial fibrosis and […]

Methods and pharmaceutical compositions for the treatment of

The present invention relates to methods and pharmaceutical compositions for the treatment of age-related cardiometabolic diseases. In particular, the […]

Use of b cell depleting agents for the treatment of rheumatic heart

Rheumatic heart disease (RHD) ranks as one of the most serious cardiovascular scourges of the past century and remains a force to be reckoned with in […]

Methods for improving relaxation of striated myocytes

The Inventors developed conditions allowing to efficiently detect differences in cardiomyocytes relaxation phases associated with increased […]

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