Antigenic peptides for the diagnosis and treatment of type 1 diabetes

Despite the notion that human CD8+ T cells are the final mediators of autoimmune ?-cell destruction in type 1 diabetes (T1D), none of their target […]

Bacteroides faecichinchilleae and its use in the treatment of

The invention relates to the field of probiotic and in particular to bacteria of the species Bacteroides faecichinchilleae and its use for treating […]

Methods and pharmaceutical compositions for inducing immune tolerance

The present invention relates to methods and pharmaceutical compositions of inducing immune tolerance by mucosal vaccination with Fc-coupled antigens. […]

Antigenic peptides deriving from pcsk2 and uses thereof for the

Despite the notion that human CD8+ T cells are the final mediators of autoimmune ?-cell destruction in type 1 diabetes (T1D), none of their target […]

Antigenic peptides deriving from urocortin 3 and uses thereof for the

Despite the notion that human CD8+ T cells are the final mediators of autoimmune ?- cell destruction in type 1 diabetes (T1D), none of their target […]

Antigenic peptides deriving from secretogranin v and uses thereof for

Despite the notion that human CD8+ T cells are the final mediators of autoimmune ?- cell destruction in type 1 diabetes (T1D), none of their target […]

Use of shp2 inhibitors for the treatment of insulin resistance

Despite reaching an epidemic status worldwide, metabolic disorders, notably diabetes, still miss efficient and specific therapeutic strategies because […]

Methods and pharmaceutical compositions for the treatment of chronic

The present invention relates to methods and pharmaceutical compositions for the treatment of chronic kidney disease. The inventors used the CMap […]

Gaba administration induces alpha cell-mediated beta-like cell

GABA is an inducer of ?-to-?-like cell conversion in vivo. This conversion induces ? cell replacement mechanisms through the mobilization of […]

Methods of enhancing the potency of incretin-based drugs in subjects

The present invention relates to methods of enhancing the potency of incretin-based drugs in subjects in need thereof. Through different animal […]