Methods and pharmaceutical compositions for inducing immune tolerance by mucosal vaccination with fc-coupled antigens

The present invention relates to methods and pharmaceutical compositions of inducing immune tolerance by mucosal vaccination with Fc-coupled antigens. In particular, the present invention relates to a method for inducing tolerance to one antigen of interest in a subject in need thereof, comprising the mucosal administration to the subject of a therapeutically effective amount of a recombinant chimeric construct comprising a FcRn targeting moiety and an antigen-containing moiety.

Patent Application number: European Procedure (Patents) (EPA) - 17 Juil. 2015 - 15 306 169.2
Inventors:
GUPTA NimeshCULINA SlobodanLACROIX-DESMAZES Sébastien

Reference:

BIO15274-T1

Business Developper
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Aymeric Empereur
Business Developer
Patent filling date: 17-07-2015
Rare disease: No
Second indication: No

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