Mouse anti-human lat (linker for activation of t cells) (clone lat. 10-17)

- This antibody recognizes the LAT-adaptor protein expressed on T-cells, mast cells and megacaryocytes.
- Suitable for use on paraffin sections

Interest / Relevance: - diagnosis of T-cell lymphomas
- diagnosis of mastocytosis
- useful in the diagnosis of proliferations develop from megacaryocytes

Scientist's name: Georges DELSOL
Mohamad Talal AL SAATI,Bernard PAYRASTRE

Publications:

Ragab A, Séverin S, Gratacap MP, Aguado E, Malissen M, Jandrot-Perrus M, Malissen B, Ragab-Thomas J, Payrastre B.
Roles of the C-terminal tyrosine residues of LAT in GPVI-induced platelet activation: insights into the mechanism of PLC gamma 2 activation. Blood. 2007 Oct 1;110(7):2466-74

Tedoldi S, Paterson JC, Hansmann ML, Natkunam Y, Rüdiger T, Angelisova P, Du MQ, Roberton H, Roncador G, Sanchez L, Pozzobon M, Masir N, Barry R, Pileri S, Mason DY, Marafioti T, Horejsí V.
Transmembrane adaptor molecules: a new category of lymphoid-cell markers.Blood. 2006 Jan 1;107(1):213-21

Reference:

RT00389

Type of research tool: Antibodies

Therapy area(1): Oncology

Therapy area(2): Immunology

Uses(1): Academic Research

Uses(2): Diagnostic

Inserm Transfert
Research Tools

E-mail

Clones available: LAT. 10-17

Isotype: lgG1

Source: Mouse

Specificity: Human

Immunogen Seq ID: LAT recombinant protein

Cellular Distribution: T-cell, mast cells and megacaryocytes

Know Cross Reactivity: mast cells and megacaryocytes

FBS: 15%

Rare disease: No

Last update: 11/09/2024

Mouse anti-human lat (linker for activation of t cells) (clone lat. 10-17)

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