Mouse anti-human follicular dendritic cells (clone cna.42)

Follicular dendritic cells (FDCs) are large cells in germinal centers (GCs) of primary and lymphoid tissues. They present non-processed antigen and switch off apoptosis of B cells through a selection process resulting in selection of memory B cells. They express many B cell markers such as CD21 (long isoform), CD23 and CD35. The hybridoma CNA.42 recognizes a unique carbohydrate epitope found on FDCs from a variety of species. It has been shown to be a useful reagent for both flow cytometry and IHC analysis.

Interest / Relevance: Immunoprecipitation : +
Immunofluorescence : not tested
Western Blot : +
Parafin : +
ELISA : not tested
Field of use : Immunohistochemistry : Reacts with FDC and FDC-derived tumours on paraffin-embedded tissue sections.
Keywords: FDC
Scientist's name: Georges DELSOL

Reference:

RT00166

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Georges DELSOL
Inserm Transfert
Research Tools
Clones available: CNA.42
Isotype: lgM
Source: Mouse
Specificity: Human
Cellular Distribution: CEM T-cell leukeamia cell line - mymphoma cell line
FBS: FBS : 15% ATCC/CNCM : ATCC CCL 119
Rare disease:
Last update: 29/09/2022

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