Mouse anti-Human ADAM10 (a disintegrin and metalloprotease domain 10) (clone 11G2)

Mammalian disintegrin-metalloproteasem Kuzbanian protein homolog, CDw156, Disintegrin and metalloproteinase domain-containing protein 10

Interest / Relevance: FACS, immunostaining (frozen section, fixed cells), IP, WB

Scientist's name: Eric RUBINSTEIN
Martine BILLARD

Publications:

1) Jouannet S, Saint-Pol J, Fernandez L, Nguyen V, Charrin S, Boucheix C, Brou C, Milhiet PE, Rubinstein E. TspanC8 tetraspanins differentially regulate the cleavage of ADAM10 substrates, Notch activation and ADAM10 membrane compartmentalization. Cell. Mol. Life Sci. (2016) 73:1895–1915.

2) Dornier E, Coumailleau F, Ottavi JF, Moretti J, Boucheix C, Mauduit P, Schweisguth F and Rubinstein E. TspanC8 tetraspanins regulate the trafficking of ADAM10/Kuzbanian and Notch receptor activation in flies and mammals. J Cell Biol. 2012, 199:481-496.

3) Arduise C, Abache T, Lei Li, Billard M, Chabanon A, Ludwig A, Mauduit P, Boucheix C, Rubinstein E, Le Naour F. Tetraspanins regulate ADAM10-mediated cleavage of TNF? and EGF. J. Immunol. 2008, 181: 7002-7013

Reference:

RT00070

Type of research tool: Antibodies

Therapy area(1): Central Nervous System

Uses(1): Academic Research

Uses(2): Industry Research (screening, tox.studies, bioreactor, ...)

Inserm Transfert
Research Tools

E-mail

Clones available: 11G2

Isotype: lgG1

Source: Mouse

Specificity: Human

Rare disease: No

Last update: 11/09/2024

Mouse anti-Human ADAM10 (a disintegrin and metalloprotease domain 10) (clone 11G2)

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