Use of shp2 inhibitors for inhibiting senescence

/t/t/u25cb According to the WHO, the population aged 60 and over will have doubled by 2050. Unfortunately, aging comes along with an explosion of […]

Method and pharmaceutical composition for use in the treatment of

The present invention relates to the treatment of nutritional liver diseases or metabolic syndrome. In this study, the inventors aimed to identify […]

A breast-cancer cell line expressing a bret biosensor to monitor pi-3

We have developed a MCF7-derived cell line stably co-expressing the pleckstrin homology (PH) domain of Akt fused to Renilla luciferase (Luc-Akt-PH) […]

Nanoparticle based glue, biocompatible sealant for surgery

The present invention relates to methods for adhering tissue surfaces and materials and biomedical uses thereof. In particular the present invention […]

Improved vector for driving the targeted integration of a transgene

The present invention relates to polypeptide for engineering integrase chimeric proteins and their use in gene therapy. A key challenge for gene […]

Ctip fusion to cas9 enhances transgene integration by

The present invention relates to nuclease protein fusions for enhancing genome editing by homology-directed transgene integration (HDI).The inventors […]

Mouse anti-human/mouse/ rat tspan5 (clones ts5-2 and ts5-3)

This mAb recognizes Tspan5, a member of the Tetraspanin superfamily. It recognizes the human, mouse and rat proteins which are 100% identical. First […]

Chimeric receptor for use in whole-cell sensors for detecting analytes

The present invention relates to chimeric receptors that can be used in whole-cell sensors for detecting analytes of interest. The inventors showed […]

Rat mesothelial cell line f2-3

Transformed rat mesothelial cell line isolated from the peritoneal fluid of a female rat (Fischer F344) after 313 days of induction with crocidolite […]

Rat mesothelial cell line f2-4

Transformed rat mesothelial cell line isolated from the peritoneal fluid of a female rat (Fischer F344) after 347 days of induction with crocidolite […]