Targeting myeloperoxidase overcomes cytarabine resistance in human

Chemotherapy commonly alters cellular redox balance and increases the oxidative state. Recent studies have reported that chemoresistant cells have an […]

Enhancement of 5-fluorouracil cytotoxicity by pyridoxal 5’-phosphate

The invention relates to methods and pharmaceutical compositions for treating cancer in a subject in need thereof. The inventors thought that low […]

Inhibition of nicotinamide phosphoribosyltransferase (nampt) for the

The present invention relates to a method for treating a subject suffering from melanoma resistant by administering to said subject an inhibitor of […]

A checkpoint kinase 1 inhibitor sensitises cancer cells to

The present invention relates to the field of cancer treatment. In this study, the inventors sought to investigate whether this antiproliferative […]

Inhibition of usp14 impairs melanoma cell survival and overcomes

The present invention relates to a method and composition for treating melanoma. More particularly, inventors have shown that high expression of USP14 […]

Predicting the risk of having hepatocellular carcinoma in cirrhosis

Plasma levels of different sub-populations of microvesicles (endothelial, leukocyte, platelet and hepatocyte) were measured by flow cytometry or ELISA […]

Slitrk6 as a target for cancers associated with activation of the mapk

The response of subjects suffering from cancer to MAPK inhibitors is dramatically impaired by secondary resistances and rapid relapse. So far, the […]

Device for monitoring the density of a sample and associated method

The invention concerns the field of measuring the density of a sample, notably for evaluating the relative amount of the first component and the […]

Nano-sized drug delivery structure

The present invention relates to a nano-sized drug delivery structure for delayed and controlled diffusion of at least one drug active, in particular […]

Optical fiber mode scrambler

The invention relates to a fiber optic mode scrambler component and method of making the same.This scrambler converts a Gaussian intensity profile of […]