Safety and efficacy of mait cells for adoptive cell therapy prevention

The inventors explored in an allogeneic situation the regulatory potential of Mucosal-Associated Invariant T cells (MAIT cells), a population of […]

Methods for the diagnosis and thetreatment of graft-versus-host

The invention relates to methods for the prediction and the treatment of risk of acute graft versus host disease. The inventors demonstrated that an […]

Use of etv3 or etv6 inhibitors for blocking the differentiation of

In inflamed tissues, monocytes differentiate into macrophages (mo-Mac) or dendritic cells (mo-DC). In chronic non-resolving inflammation, mo-DC are […]

Fc-engineered anti-human ige antibodies and methods of use

The present invention relates to the treatment of IgE-mediated disease. The inventors hypothesized that formation of immune complexes between […]

Methods for modulating innate lymphoid cell activity, antibody drug

The present invention relates to methods for modulating innate lymphoid cell activity, antibody drug conjugates and uses in therapy. The inventors […]

Use of tcr-deficient car-tregs in combination with anti-tcr complex

The present invention is defined by the claims. In particular, the present invention relates to the use of TCR-deficient CAR-Tregs in combination with […]

Method for diagnosing collagen degradatation associated disease

The Inventors have developed an ELISA of a new molecular marker detecting a neoepitope generated from the cleavage of the α1 chain of type III […]

New method to diagnose inflammatory diseases

The present invention relates to the diagnostic of inflammatory diseases. The inventors described methods using NET biomarkers as diagnostic […]

Nanobody against ela2a to treat inflammatory bowel diseases (ibd) or

The invention is in the field of therapy of gut inflammatory diseases such as Inflammatory Bowel Diseases (IBD) or Irritable Bowel Syndrome (IBS) […]

Targeting the secreted ige poly-a signal allows specific inhibition of

Immunoglobulins (Ig) are expressed either on the surface of B cells or as secreted antibodies by plasma cells that represents the final stage of B […]