We introduced the Prkcd G510S mutation that we previously associated to a Mendelian cause of SLE in the mouse genome, by means of CRISPR-Cas9 gene […]
The invention relates to methods for the prediction and the treatment of risk of acute graft versus host disease. The inventors demonstrated that an […]
The Bd37 is an erythrocyte binding protein anchored at the surface of the parasite Babesia divergens. B. divergens is an Apicomplexa parasite, mostly […]
The present invention relates to allergy field. Several independent groups have recently investigated the implication of PCSK9 on inflammation and […]
The present invention relates to the field of organ transplant and the issues associated with transplant rejection. Antibody-mediated rejection (AMR) […]
Expression vectors encoding human cellular fibronectin variants harboring the alternatively spliced Extra Domains B and/or A (or neither) ; […]
CD4 T cell help is essential to promote robust cytotoxic T cell responses and could be harnessed to improve outcomes of cancer immunotherapy. To […]
The present invention relates to a PAK-1 and/or PAK-2 inhibitor for use in the treatment of NLRP3 inflammasome mediated IL-1beta dependent disorders […]
The present relates to interleukin 15 (IL-15) antagonists and uses thereof, in particular for the treatment of autoimmune diseases and inflammatory […]