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GABA is an inducer of ?-to-?-like cell conversion in vivo. This conversion induces ? cell replacement mechanisms through the mobilization of […]
In diabetic retinopathy, the exact mechanisms leading to retinal capillary closure and to retinal barriers breakdown remain imperfectly understood. […]
The invention relates to generation, optimization and characterisation of VHH targeted against Tau MTBD (microtubule-binding domain) with high […]
The present invention relates to the field of memory and cognitive functions. Here the inventors show that memory stimulations induce autophagy in the […]
The present invention is directed to novel compounds and pharmaceutically acceptable salts or solvates thereof, and their use. […]
The invention relates to methods and pharmaceutical compositions for treating cancer in a subject in need thereof. The inventors thought that low […]
Worldwide, 1% to 2% of the general adult population have heart failure (HF), which is accompanied by reduced quality of life, high morbidity, […]
The present invention relates to the field of cancer treatment. In this study, the inventors sought to investigate whether this antiproliferative […]
The invention is based on the discovery of a new bacterial compound with analgesic properties which could be used as a new tool for the treatment of […]
In the present invention it is shown that the inactivation of the Pyk2 gene does not alter hippocampal development but prevents hippocampal-dependent […]