Back to results

Mouse anti-human melanoma associated antigen (clone pnl2)

- this new monoclonal antibody is directed against a new fixative resistant melanocyte/melanoma-associated antigen.
- PNL2 labels more than 70% of neoplastic cells in all primary melanomas irrespective of their histologic type. All metastatic melanomas are also stained
Interest / Relevance: - diagnosis of primary and metastatic melanomas
Scientist's name: Georges DELSOL
Laurence LAMANT-ROCHAIX,Mohamad Talal AL SAATI
Publications:
PNL2, a new monoclonal antibody directed against a fixative-resistant melanocyte antigen. Rochaix P, Lacroix-Triki M, Lamant L, Pichereaux C, Valmary S, Puente E, Al Saati T, Monsarrat B, Susini C, Buscail L, Delsol G, Voigt JJ.
Mod Pathol. 2003 May;16(5):481-90.

Reference:

RT00377

Business Developper
contact
Inserm Transfert
Research Tools
Clones available: PNL2
Isotype: lgG1
Source: Mouse
Specificity: Human
Immunogen Seq ID: Somatostatin receptor subtype 2 recombinant protein (probably a mouse melanocyte auto-antibody)
Cellular Distribution: Skin and oral mucosae melanocytes, Reacts with granulocytes when used at high concentration.
Know Cross Reactivity: granulocytes. PNL2,stained most of the clear cell sarcoma cells, and a few cells in angiomyolipomas
FBS: 15%
Rare disease: No
Last update: 11/09/2024

You might also be interested in

RT00399

Transgenic mouse model for myotonic dystrophy:

This transgenic mice model contains large human genomic DNA sequence carrying the DMPK gene with […]

Read more
RT00344

Rat anti-mouse cd26 (mouse dipeptidyl peptidase

Rat monoclonal antibody recognizing the cell surface antigen DPP IV (CD26) involved in T cell […]

Read more
RT00480

Gfp-tagged mucin-reporter mouse model

To follow the Muc5b gel-forming mucin production, we tagged with a GFP variant the corresponding […]

Read more
RT00394

Rbl-2h3 rat mast cell line : in vitro

Rat mast cell line (RBL-2H3) transfected with the cDNAs encoding the three subunits (alpha, beta, […]

Read more
RT00286

Mouse anti-histone h1zero (clone 27e8e10)

[…]

Read more
RT00287

Mouse anti-histone h1zero (clone 34b10h4)

[…]

Read more
RT00320

Mouse anti mouse ccl5 monoclonal antibody (clone

Mouse monoclonal antibody directed against mouse CCL5.
Antibody was produced by immunising CCL5 […]

Read more
RT00469

Human ferroportin polyclonal antibodies

Rabbit Polyclonal antibodies raised against 3 differents portions of the iron exporter Human […]

Read more
RT00488

Technique to isolate live renal proximal tubular

We isolate renal proximal tubular cells using the proximal tubular marker Prominin-1.
We use a […]

Read more
RT00486

Primary cultures of mice proximal tubular cells

Proximal tubular cells are isolated by magnetic sorting coupled with microbeads-conjugated […]

Read more
RT00559

Hg5ln gal4-hppar gamma cell line

HG5LN were generated by transfection of cervical cancer HeLa cells with the […]

Read more
RT00005

Cpt1 expressing yeast strains

Saccharomyces cerevisiae expressing under the GAL promoter either the wild-type rat liver CPT1, […]

Read more