Use of new biomarker for selecting and determining response to

Exercise improves metabolic health and prevents the complications of obesity and type 2 diabetes. The inventors hypothesized that skeletal muscle […]

Methods of determining whether a subject is at risk of developing

Proprotein convertase subtilisin/kexin type 9 (PCSK9) binds low-density lipoprotein receptor (LDLR), preventing its recycling. PCSK9 is a risk […]

Method for early prediction of neurodegenerative decline

The present invention relates to a method for predicting risks of neurodegenerative decline of a patient, especially of mild cognitive impairment […]

Methods for predincting the risk of developing pulmonary

The present invention relates to methods for predicting the risk of developing pulmonary colonization/infection by P. aeruginosa. The inventors […]

Gfi1 as a new target for the treatment of hyperglycemia and diabetes

Gfi1 is expressed in the pancreas, starting from the first stages of pancreatic embryonic development. Conditional knock out Gfi1 (exclusively in the […]

Use of shp2 inhibitors for the treatment of insulin resistance

Despite reaching an epidemic status worldwide, metabolic disorders, notably diabetes, still miss efficient and specific therapeutic strategies because […]

Methods and pharmaceutical compositions for the treatment of chronic

The present invention relates to methods and pharmaceutical compositions for the treatment of chronic kidney disease. The inventors used the CMap […]

Use of pi3kc2¿ inhibitors for the preservation of vascular

Ischemic conditions are a leading cause of death for both men and women. Ischemia, a condition characterized by reduced blood flow and oxygen to an […]

Neutralizing granzyme b for providing cardioprotection in a subject

The present invention relates to a method for providing cardioprotection in a subject who experienced a myocardial infarction comprising administering […]

Mouse anti-human/mouse/rat tspan5 (clones ts5-2 and ts5-3)

This mAb recognizes Tspan5, a member of the Tetraspanin superfamily. It recognizes the human, mouse and rat proteins which are 100% identical. First […]

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