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TSSP is a novel protease suspected to edit the peptide repertoire presented by MHC class II molecules in the thymus. Prss16, the gene coding for TSSP […]
Uncoupling protein (UCP) 3 is a mitochondrial inner membrane protein expressed predominantly in glycolytic skeletal muscles.Transgenic mice were […]
This transgenic mice model ("DMSXL") contains large human genomic DNA sequence carrying the DMPK gene with very large repeat (>1200 CTG). […]
Transgenic mouse model carrying the myotonic dystrophy type 1 (DM1) locus (45kb of human sequences) with the DMPK gene and about 300 unstable CTG […]
We can provide mice a nutritional model of mice which become either type 2 diabetic without obesity, or obese and diabetic or mainly obese. […]
This mouse is deficient for TP53INP1 (both isoforms TP53INP1alpha and TP53INP1beta). TP53INP1 is a key stress factor endowed with a tumor suppressor […]
mouse exhibiting a Lox-APL transgene leading to a tissue specific invalidation. […]
The class B, type I scavenger receptor (Srb1 or Scarb1) is a cell surface HDL receptor. It plays a key role in determining the levels of plasma […]
To follow a gel-forming mucin production, we tagged with a GFP variant a mouse mucin gene. This reporter mouse allow also to follow goblet cell number […]
We introduced the Prkcd G510S mutation that we previously associated to a Mendelian cause of SLE in the mouse genome, by means of CRISPR-Cas9 gene […]
We introduced the Prkcd G510S mutation that we previously associated to a Mendelian cause of SLE in […]
Transgenic mouse model carrying the myotonic dystrophy type 1 (DM1) locus (45kb of human sequences) […]
Amyloidosis is a rare disease caused by extracellular deposition of insoluble abnormal fibrils […]
This mouse is deficient for TP53INP1 (both isoforms TP53INP1alpha and TP53INP1beta). TP53INP1 is a […]
Invalidation of apelin in adipose tissue with an aP2CRE-LoxAPL mouse […]
These germ free mice are colonized with human microflora and fed a high fat diet which allows the […]
The mice are hemizygous for the human apolipoprotein A2 (ApoA2) gene expressed under the control of […]
TPM3-ALK (Tropomyosin 3-Anaplastic lymphoma kinase) is oncogenic tyrosine kinase implicated in the […]
To follow a gel-forming mucin production, we tagged with a GFP variant a mouse mucin gene. This […]
TSSP is a novel protease suspected to edit the peptide repertoire presented by MHC class II […]
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