New method for producing Outer Membrane Vesicles by hlyF-expressing E coli strains as vaccine component
The present invention relates to a method for producing outer membrane vesicles (OMVs) by expression or overexpression of the hemolysin F gene (hlyF) in gram-negative bacterium for use as vaccination vector.
- J Infect Dis. 2016 Mar 1;213(5):856-65. doi: 10.1093/infdis/jiv506. Epub 2015 Oct 22.