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Nanoblade technology: high efficiency delivery of crisprs components in primary cells by virus like particles.

The present invention relates to a virus-derived particle comprising one or more Cas protein(s), as well as to kits and methods using the same for altering a target nucleic acid.

Keywords: CRISPR, Cas9, Virology, Gene editing, Gene therapy

Publications:

Efficient genome editing in primary cells and in vivo using viral-derived ’Nanoblades’ loaded with Cas9/sgRNA ribonucleoproteins https:/www.biorxiv.org/content/early/2017/10/12/202010

Reference:

BIO15247-T1

Inserm Transfert
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Patent filling date: 20-10-2015

Rare disease: No

Second indication: No

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