Gene therapy approach combined to chemotherapy for improving treatment of cancer

The present invention concerns products containing (i) at least one nucleic acid sequence coding for the human somatostatin 2 receptor protein (sst2), (ii) at least one nucleic acid sequence coding for the human deoxycytidine kinase protein (dck), (iii) at least one nucleic acid sequence coding for the human uridine monophosphate kinase protein (umk) and (iv) gemcitabine, as a combined preparation for simultaneous, separate, or sequential use for treating cancer in a subject.

Keywords: Gene therapy, cancer, clinic,
Patent Application number: EP 07301447.4
Inventors:
Gérard TIRABYLouis BUSCAILFabienne VERNEJOULDaniel DROCOURTChristiane SUSINI
Publications:
Buscail L et al. Mol Ther. 2015 Apr;23(4):779-89

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