therapeuticpublished patents
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Infectious diseases
The present invention relates to allergy field. Several independent groups have recently investigated the implication of PCSK9 on inflammation and […]
The response of subjects suffering from cancer to MAPK inhibitors is dramatically impaired by secondary resistances and rapid relapse. So far, the […]
Inventors have generated two human anti-cath-D scFv fragments cloned in the human IgG1 format (F1 and E2) that efficiently bind to human and […]
Chronic obstructive pulmonary disease (COPD) remains a major cause of morbidity and mortality worldwide. Acute exacerbation of COPD (AE-COPD) in […]
New anti-atherogenic strategies based on B cell modulation, and suggest that patients currently treated with CD20 antibodies for other immune-mediated […]
The present invention relates to anti-protease nexin-1 (PN-1) conformational single domain antibodies and uses thereof in particular in the […]
Obesity is associated with low-grade inflammation in adipose tissue (AT) and dysfunctional adipocytes producing inflammatory molecules. A recent study […]
The present invention relates to a neutralising antibody which is capable of binding to neurotensin with high affinity. The antibody of the present […]
The present invention relates to human monoclonal antibodies against orexin receptor type 1 (OX1R) and uses thereof for the treatment of cancer. […]
Here the inventors show, using in vivo imaging and viral approaches, that calcium released by […]
In the present invention it is shown that the inactivation of the Pyk2 gene does not alter […]
In the present invention it is shows that the inactivation of the Pyk2 gene does not alter […]
The present invention relates to a method for treating a subject suffering from a cancer comprising […]
HSP110 is involved in multiple tumorigenic processes, but no inhibitor was known to date. The […]
The present invention relates to the treatment of idiopathic pulmonary fibrosis. Today, there is no […]
Anthracyclines such as doxorubicin are chemotherapeutic molecules are also widely incorporated in […]
The present invention relates to methods and pharmaceutical compositions for the treatment of […]
Inventors have surprisingly found that Emricasan is a much more potent inhibitor of monocyte […]
Heart failure with preserved ejection fraction (HFpEF) which results from diastolic dysfunction is a […]
The present invention relates to a genetically modified hematopoietic stem cell (HSC) comprising, […]
The growing prevalence of obesity and type 2 diabetes complicates risk and clinical management by […]
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