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therapeuticpublished patents
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Complement components form a plasma innate immune cascade but could also serve as multitasking proteins, as they have functions beyond this system. […]
The present invention relates to the stratification and treatment of patients suffering of cancer. Due to the fact that anti-PD1 therapy targets […]
The inventors found that metabolic gene signatures of human pan-tumor associated myeloid cells correlate with patient survival and cancer cell mitotic […]
The present invention relates to use of soluble CD27 as a biomarker to predict the reponse to an immune checkpoint inhibitor treatment. Inventors have […]
Renal Cell Carcinoma (RCC) encompasses a heterogeneous group of cancers derived from renal tubular epithelial cells and has a worldwide mortality. […]
Kidney cancer also called 'renal cancer,' or ' renal cell carcinoma' (RCC) refers to cancer that has arisen from the kidney, and is by far the most […]
Lung cancer is the most common cause of cancer related death in the world. Approximately 80% to 90% of cases involve Non–Small-Cell Lung Cancer […]
The response of subjects suffering from cancer to MAPK inhibitors is dramatically impaired by secondary resistances and rapid relapse. So far, the […]
Here the inventors show, using in vivo imaging and viral approaches, that calcium released by […]
In the present invention it is shown that the inactivation of the Pyk2 gene does not alter […]
In the present invention it is shows that the inactivation of the Pyk2 gene does not alter […]
The present invention relates to a method for treating a subject suffering from a cancer comprising […]
HSP110 is involved in multiple tumorigenic processes, but no inhibitor was known to date. The […]
Anthracyclines such as doxorubicin are chemotherapeutic molecules are also widely incorporated in […]
The present invention relates to the treatment of idiopathic pulmonary fibrosis. Today, there is no […]
The present invention relates to methods and pharmaceutical compositions for the treatment of […]
Heart failure with preserved ejection fraction (HFpEF) which results from diastolic dysfunction is a […]
Inventors have surprisingly found that Emricasan is a much more potent inhibitor of monocyte […]
The present invention relates to a genetically modified hematopoietic stem cell (HSC) comprising, […]
The growing prevalence of obesity and type 2 diabetes complicates risk and clinical management by […]
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