147

therapeutic
published patents

56

oncology
published patents

310

research tools

46

diagnostic
published patents

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Use of ngal inhibitors for treating chronic wound

Chronic wounds and in particular diabetic ulcers are a serious complication of diabetes. Unresolved inflammation, associated with the dysregulation of […]

Cb1 receptor antagonist for the treatment of liver fibrosis

CB1 were highly induced in human cirrhotic samples and in liver fibrogenic cells. Treatment with specific CB1 antagonist decreased the wound-healing […]

Inhibition of usp14 impairs melanoma cell survival and overcomes

The present invention relates to a method and composition for treating melanoma. More particularly, inventors have shown that high expression of USP14 […]

Inhibition of nicotinamide phosphoribosyltransferase (nampt) for the

The present invention relates to a method for treating a subject suffering from melanoma resistant by administering to said subject an inhibitor of […]

A lyn kinase activator for the treatment of braf inhibitor-resistant

The present invention relates to method and composition for treating melanoma. The inventors have shown that a decrease in LYN expression, in melanoma […]

Methods and pharmaceutical compositions for cardiac regeneration

The adult mammalian heart regeneration is largely prevented by the limited proliferative capacity of the resident cardiomyocytes (CMs). Here, the […]

Trpv2 as a new therapeutic target to modulate blood brain barrier

The present invention relates to a method for modulating blood-brain barrier (BBB) in a subject comprising a step of administering said subject with a […]

Microglia targeting improves cmv-related neurological outcomes

The present invention relates the field of CMV and CMV related diseases. Using a powerful rat model of CMV infection of the embryonic brain, the […]

Trek1/trek2 as targets for the treatment of migraine

Inventors have found that the MT mutation puts an alternative start codon in frame which leads to the translation of a second TRESK fragment. […]

A microrna switch regulates the rise in hypothalamic gnrh production

A method for diagnosing a reproduction-related disorder in an individual, comprising: a) measuring the level of a miR200 nucleic acid and/or miR155 […]

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