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therapeuticpublished patents
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Infectious diseases
The clinical severity of β-hemoglobinopathies is alleviated by the co-inheritance of genetic mutations causing a sustained fetal γ-globin chain […]
The present invention relates to a neutralising antibody which is capable of binding to neurotensin with high affinity. The antibody of the present […]
Despite the notion that human CD8+ T cells are the final mediators of autoimmune β- cell destruction in type 1 diabetes (T1D), none of their target […]
Despite the notion that human CD8+ T cells are the final mediators of autoimmune β-cell destruction in type 1 diabetes (T1D), none of their target […]
The present invention relates to human monoclonal antibodies against orexin receptor type 1 (OX1R) and uses thereof for the treatment of cancer. […]
Immunoglobulins (Ig) are expressed either on the surface of B cells or as secreted antibodies by plasma cells that represents the final stage of B […]
The Inventors developed conditions allowing to efficiently detect differences in cardiomyocytes relaxation phases associated with increased […]
The invention related to metabolically stable Apelin analogs and their use for the prevention or the treatment of diseases mediated by the apelin […]
Bile salts are steroid acids derived from cholesterol in the liver, are released into the gastrointestinal tract to aid in digestion and are […]
Here the inventors show, using in vivo imaging and viral approaches, that calcium released by […]
In the present invention it is shown that the inactivation of the Pyk2 gene does not alter […]
In the present invention it is shows that the inactivation of the Pyk2 gene does not alter […]
The present invention relates to a method for treating a subject suffering from a cancer comprising […]
HSP110 is involved in multiple tumorigenic processes, but no inhibitor was known to date. The […]
The present invention relates to the treatment of idiopathic pulmonary fibrosis. Today, there is no […]
Anthracyclines such as doxorubicin are chemotherapeutic molecules are also widely incorporated in […]
The present invention relates to methods and pharmaceutical compositions for the treatment of […]
Heart failure with preserved ejection fraction (HFpEF) which results from diastolic dysfunction is a […]
Inventors have surprisingly found that Emricasan is a much more potent inhibitor of monocyte […]
The present invention relates to a genetically modified hematopoietic stem cell (HSC) comprising, […]
The growing prevalence of obesity and type 2 diabetes complicates risk and clinical management by […]
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