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Method for assessing diseases associated with a loss of p53 function

The present invention relates to a method for predicting the survival time and/or the disease severity in a subject suffering from a disease […]

Methods of treating familial adenomatous polyposis

Familial adenomatous polyposis (FAP) patients harbor mutations in the APC gene and will develop adenoma and early colorectal cancer. Taking biopsies […]

Methods and pharmaceutical compositions for enhancing cd8+t

Targeting immune checkpoints, such as Programmed cell Death 1 (PD1), has improved survival in cancer patients by unleashing exhausted CD8+ T-cell […]

Inhibitor of the heterochromatin protein 1 (hp1) for modulating th

The present invention relates to a treatment of Th cell-associated disorders. Here, theinventors The inventors show that Treg-dependent suppressive […]

Methods for the diagnosis and treatment of acute lymphoblastic

The present invention relates to a method of treating acute lymphoblastic leukemia in a patient in need thereof comprising administering to the […]

B6bc cell line

This murine cell line is the first syngenic hormone receptor-positive cell line of C57BL/6 strain. The cell line can be transplanted to C57BL/6 female […]

Anti-neurotensin long fragment and anti-neuromedin n long fragment

The present invention relates to an antibody, which is capable of binding to theNeuromedin N long fragment, and Neurotensin long fragment with high […]

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