Mouse models of amyloidosis

Amyloidosis is a rare disease caused by extracellular deposition of insoluble abnormal fibrils derived from aggregation of a misfolded variant of a […]

Tp53inp1-deficient mouse

This mouse is deficient for TP53INP1 (both isoforms TP53INP1alpha and TP53INP1beta). TP53INP1 is a key stress factor endowed with a tumor suppressor […]

Germ free humanized diabetic/obese mice

These germ free mice are colonized with human microflora and fed a high fat diet which allows the study of the impact of pre and probiotics on the […]

Conditional tpm3-alk transgenic mice

TPM3-ALK (Tropomyosin 3-Anaplastic lymphoma kinase) is oncogenic tyrosine kinase implicated in the pathogenesis of human ALK-positive lymphoma. We […]

Gfp-tagged mucin-reporter mouse model

To follow the Muc5b gel-forming mucin production, we tagged with a GFP variant the corresponding gene. This reporter mouse allows to follow goblet […]

Selective antiestrogen binding site (aebs) ligands in the diphenyl

We can offer and produce selective AEBS lignads for research purpose only.These compounds are potent inducers of breast cancer cell differentiation […]

Highly differentiated human hepatocytes in primary culture

Hepatocytes are isolated from human liver and cultured in a system that allows to maintain a highly differentiated phenotype for several weeks.In […]

Apoa2 humanized transgenic mouse – line beta

The mice are hemizygous for the human apolipoprotein A2 (ApoA2) gene expressed under the control of the homologous promoter (-911/+2045). They are […]

High-throughput screening for small psycho-active molecules in

Here, we describe a simple, behaviour-based approach to identify in vivo novel psycho-active molecules in zebrafish embryos. Using an automated […]

Apoa2 humanized transgenic mouse – line delta

The mice are hemizygous for the human apolipoprotein A2 (ApoA2) gene expressed under the control of the homologous promoter (-911/+2045). They are […]