Methods for the diagnosis and treatment of t cell-lymphomas ccr8

T-cell lymphomas are a heterogeneous group of malignancies involving T lymphocytes and generally characterized by a poor prognosis. Among them, […]

Anti-robo4 human monoclonal antibodies and usesthereof for the

There is an interest to develop anti-ROBO4 antibodies that can be suitable for the treatment of cancer. The inventors produced new human antibodies […]

Methods and pharmaceutical compositions for treating cancer

Tumour-specific molecular targets and alternative therapeutic strategies for triplenegative breast cancer (TNBC) are urgently needed. The protease […]

Anti-mÜllerian inhibiting substance antibodies and uses thereof

In ovarian carcinoma, Müllerian Inhibiting Substance (MIS) type II receptor (MISRII) and the MIS/MISRII signaling pathway are potential therapeutic […]

Bispecific antibody targeting transferrin receptor 1 and soluble

The invention relates to a bispecific antibody targeting TfR1 and a soluble antigen. The inventors demonstrate that the unique mode of interaction of […]

Novel target and mab candidates for the treatment of hcmv infection

The present invention relates to a method for treating an infection, particularly HCMV infection. To date, there are very few reports on the role of […]

Use of an agent capable of inhibiting the activation of mait cells for

Obesity is associated with low-grade inflammation in adipose tissue (AT) and dysfunctional adipocytes producing inflammatory molecules. A recent study […]

Anti- protease nexin-1 conformational single domain antibodies and

The present invention relates to anti-protease nexin-1 (PN-1) conformational single domain antibodies and uses thereof in particular in the […]

Antibodies specific for il20-rb and uses thereof for the treatment of

Chronic obstructive pulmonary disease (COPD) remains a major cause of morbidity and mortality worldwide. Acute exacerbation of COPD (AE-COPD) in […]

Methods and compositions for treating asthma and allergic diseases

The present invention relates to allergy field. Several independent groups have recently investigated the implication of PCSK9 on inflammation and […]