The present invention relates to a method for providing cardioprotection in a subject who experienced a myocardial infarction comprising administering […]

The present invention relates to a method for treating vitiligo in a subject in need thereof comprising a step of administering to said subject a […]

The present invention relates to a PAK-1 and/or PAK-2 inhibitor for use in the treatment of NLRP3 inflammasome mediated IL-1beta dependent disorders […]

The present invention relates to the diagnosis of gastrointestinal stromal tumors (GISTs). The present invention also relates to methods and […]

The present invention relates to method and composition for treating melanoma. The inventors have shown that a decrease in LYN expression, in melanoma […]

Immune checkpoint blockade therapy is based on the inhibition of the tumor-mediated suppression of anticancer immune responses. However, the efficacy […]

The present invention relates to a method and composition for treating melanoma. More particularly, inventors have shown that high expression of USP14 […]

New anti-atherogenic strategies based on B cell modulation, and suggest that patients currently treated with CD20 antibodies for other immune-mediated […]

Inflammation is a prominent feature of ischemia-reperfusion injury (IRI) characterized by leukocyte infiltration and renal tubular injury. However, […]

The severity of renal lesions after nephron reduction varied substantially among mouse strains and required activation of EGFR. Lipocalin 2 (Lcn2, […]