Garp as a biomarker and biotarget in t-cell malignancies

The present study of the regulatory T phenotype of Sézary cells led to the discovery of the expression of GARP (LRRC32) by Sézary cells. GARP has […]

Methods for the diagnosis and treatment of acute lymphoblastic

The present invention relates to a method of treating acute lymphoblastic leukemia in a patient in need thereof comprising administering to the […]

Lrrc33 as a biomarker and biotarget in cutaneous t-cell lymphomas

The present study of the regulatory T phenotype of Sézary cells led to the discovery of the expression of LRRC33 by Sézary cells. LRRC33 therefore […]

New strategy targeting stroma/tumor cell crosstalk to treat a cancer

In this study, the Inventors report that CD9 is a key component of PC-associated CAFsderived ANXA6+-EVs. They determined that CD9 is expressed by […]

Cd38 as a biomarker and biotarget in cell-lymphomas

T-cell lymphomas are a heterogeneous group of malignancies involving T lymphocytes and generally characterized by a poor prognosis. Among them, […]

Methods and compositions for treating triple negative breast cancer

Inventors analyzed the prognostic value of tumor and stromal-derived SPARC in a large series that included 148 non-metastatic TNBC patients with a […]

Ivig composition and method of treatment of antibody deficient

The invention is in the field of therapy of antibody deficiencies such as immune diseases and inflammatory disorders. The inventors demonstrate for […]

Nanobody against ela2a to treat inflammatory bowel diseases (ibd) or

The invention is in the field of therapy of gut inflammatory diseases such as Inflammatory Bowel Diseases (IBD) or Irritable Bowel Syndrome (IBS) […]

Methods of treatment of inflammatory bowel diseases

Inventor’s general objective was to investigate the potential role of mucosal thrombin in intestinal inflammation and its mechanisms of action. […]

Use of inhibitors of phosphatase activity of soluble epoxide for the

The growing prevalence of obesity and type 2 diabetes complicates risk and clinical management by potentiating and/or exacerbating hypertension, […]