Use of the recombinant fibrinogen-like domain of angiopoietin-like 4

Microvascular leak plays a critical role in the outcome of sepsis. Counteracting vascular leakage has recently raised a huge interest in the field but […]

Methods and pharmaceutical compositions for the treatment of

Osteoarthritis (OA) is a type of degenerative joint disease that results from breakdown of joint cartilage and underlying bone. Here, the inventors […]

Methods for prediction and monitoring of spontaneous preterm birth

In the present invention, thanks to a prospective multicenter cohort study including 200 pregnant patients with five-serum sampling per patient, […]

Methods for the diagnosis and treatment of acute lymphoblastic

The present invention relates to a method of treating acute lymphoblastic leukemia in a patient in need thereof comprising administering to the […]

Modulating the expression and/or activity of gas7 for modulating viral

Macrophages (MØ) are critical for the detection and clearance of pathogens and yet also serve as replication niches for multiple infectious agents. […]

Alphavirus nsp3 helical tubular scaffolds

Alphaviruses, such as chikungunya virus (CHIKV), are mosquito-borne viruses that represent a significant threat to human health due to the current […]

Methods for the treatment of endometriosis

Endometriosis is a chronic oestrogen-dependent inflammatory disease characterised by the presence of endometrial tissue outside the uterine cavity. […]

Methods of treatment of metabolic disorders

In the present invention SLC5A9 gene (encoding SGLT4 protein) regulation was analyzed in the intestine of patients before and after weight-loss […]

Methods of prognosis and treatment of patients suffering from cancer

Lung fibroblast play an important role in lung cancer tumor microenvironment (TME). Senescence is involved in the pathophysiology of tumorogenesis. […]

Cd1a as a biomarker and biotarget in cutaneous t-cell lymphomas

The present study of the regulatory T phenotype of Sézary cells led to the discovery of the expression of CD1a by Sézary cells. CD1a therefore […]