Gram-negative bacteria efflux pump inhibitors

Antimicrobial resistance is a global problem, rendering conventional treatments less effective and requiring innovative strategies to combat this […]

New method to treat infectious diseases

The present invention relates to the treatment of infectious diseases. In this study, the inventors identified the potential protective mechanisms […]

Bacteroides faecichinchilleae and its use in the treatment of

The invention relates to the field of probiotic and in particular to bacteria of the species Bacteroides faecichinchilleae and its use for treating […]

Use of the recombinant fibrinogen-like domain of angiopoietin-like 4

Ischemic heart diseases are leading causes of death and reduced life quality worldwide. Although revascularization strategies significantly reduce […]

Hepcidin antagonists for use in the treatment of inflammation

The present invention relates to a hepcidin antagonist for use in the treatment of inflammatory diseases. TLR4-dependant intestinal hepcidin induces […]

Gpr50 ligands for use for treating diseases mediated by gpr50

GPR50 (also known as MMR, H9 or ML1X), is an orphan G protein-coupled receptorbelonging to the melatonin receptor family, but which has lost the […]

Anti-mÜllerian inhibiting substance antibodies and uses thereof

In ovarian carcinoma, Müllerian Inhibiting Substance (MIS) type II receptor (MISRII) and the MIS/MISRII signaling pathway are potential therapeutic […]

Nanoblade technology: high efficiency delivery of crisprs components

The present invention relates to a virus-derived particle comprising one or more Cas protein(s), as well as to kits and methods using the same for […]

Novel melanoma antigen peptide and uses thereof

The invention relates to peptides derived from the MELOE antigen for therapeutic vaccination against cancer. A phase I clinical trial for ex-vivo […]

Exon skipping therapy of erythropoietic protoporphyria

The present invention relates to methods and pharmaceutical compositions for the treatment of Erythropoietic Protoporphyria. In particular, the […]