Methods and compositions for treating triple negative breast cancer

Inventors analyzed the prognostic value of tumor and stromal-derived SPARC in a large series that included 148 non-metastatic TNBC patients with a […]

Methods for improving the efficacy of hdac inhibitor therapy and

Investigating the impact of Tau protein expression in cancer cell lines, Inventors have demonstrated that the Tau expression is associated with an […]

Methods and kits for identifying and quantifying storage-induced

Refrigerated storage of red cell concentrates (RCC) for transfusion is associated with the accumulation of various alterations to the red blood cells […]

Methods and compositions for modulating macrophages polarization

Inventors have surprisingly found that Emricasan is a much more potent inhibitor of monocyte differentiation compared to q-VD-OH by its ability to […]

Methods and compositions for treating pulmonary alveolar proteinosis

The present invention relates to a method for treating pulmonary alveolar proteinosis related to MARS gene mutations in a subject in need thereof […]

New method to treat acidosis related diseases

The present invention relates to the treatment of acidosis related diseases. In this study, the inventors have investigated how human monocytes adapt, […]

Use of b cell depleting agents for the treatment of rheumatic heart

Rheumatic heart disease (RHD) ranks as one of the most serious cardiovascular scourges of the past century and remains a force to be reckoned with in […]

Methods and compositions for treating cell senescence accumulation

The inventors have surprisingly demonstrated that GD3 positive senescent cells inhibit NK cell in vitro and in vivo while GD3 negative senescent cells […]

New method to evaluate pancreatic prognosis

The present invention relates to the prediction of the survival time of a patient suffering of a pancreatic cancer. In this study, the inventors aimed […]

Methods for the diagnosis and treatment of t cell-lymphomas ccr8

T-cell lymphomas are a heterogeneous group of malignancies involving T lymphocytes and generally characterized by a poor prognosis. Among them, […]