Use of vdac and lamp1 as markers for detecting pocked red blood cells

Counting vacuole-containing RBC (pocked-RBC) is a robust marker of defective spleen function but requires the expertise of fewer and fewer specialized […]

Methods for the diagnosis, prognosis and the treatment of transplant

Allogeneic kidney transplantation is a common transplant procedure and an optimal form of therapy for individuals who reach end-stage renal disease, […]

Methods of predicting the risk of recurrence and/or death of patients

Circulating tumor DNA (ctDNA) is a promising non-invasive biomarker in cancer. The inventors aim to assess the dynamic evolution of ctDNA in patients […]

Method for assessing diseases associated with a loss of p53 function

The present invention relates to a method for predicting the survival time and/or the disease severity in a subject suffering from a disease […]

Methods of treating familial adenomatous polyposis

Familial adenomatous polyposis (FAP) patients harbor mutations in the APC gene and will develop adenoma and early colorectal cancer. Taking biopsies […]

Methods and pharmaceutical compositions for enhancing cd8+t

Targeting immune checkpoints, such as Programmed cell Death 1 (PD1), has improved survival in cancer patients by unleashing exhausted CD8+ T-cell […]

Inhibitor of the heterochromatin protein 1 (hp1) for modulating th

The present invention relates to a treatment of Th cell-associated disorders. Here, theinventors The inventors show that Treg-dependent suppressive […]

Use of drugs that stiffen mature gametocytes for blocking transmission

The spleen clears rigid erythrocytes from the circulation. Drug-induced stiffening of Plasmodium falciparum intra-erythrocytic sexual stages (mature […]

Methods for the treatment of endometriosis

Endometriosis is a chronic oestrogen-dependent inflammatory disease characterised by the presence of endometrial tissue outside the uterine cavity. […]

Use of tryptophan hydroxylase 1 (tph1) inhibitors for the treatment of

Tryptophan (Trp) is one of the nine essential amino acids supplied by the diet, whose metabolism appears as a key metabolic gatekeeper of intestinal […]