Use of drugs that stiffen mature gametocytes for blocking transmission

The spleen clears rigid erythrocytes from the circulation. Drug-induced stiffening of Plasmodium falciparum intra-erythrocytic sexual stages (mature […]

Use of nrf2 activators for the treatment of cerebral small vessel

Cerebral small vessel disease (SVD) is a leading cause of stroke and a major contributor to cognitive decline and dementia in the population. […]

Methods and pharmaceutical compositions for the treatment of autosomal

Autosomal dominant polycystic kidney disease (ADPKD) is a hereditary disease affecting 1 in 1,000 to 1 in 2,500 individuals worldwide. The […]

Methods of prognosis and treatment of patients suffering from cancer

Lung fibroblast play an important role in lung cancer tumor microenvironment (TME). Senescence is involved in the pathophysiology of tumorogenesis. […]

Methods for the diagnosis, treatment and analysis ofnlrp3-associated

Using NLRP3-deficient U937 cells reconstituted with doxycycline-inducible NLRP3 variants in response to NLRP3 induction, the present inventors have […]

Methods and kits for diagnosing cause of nephrotic syndrome and

The present invention describes the identification of a soluble glomerular permeability factor, anti-Vasorin (or anti-VASN) autoantibodies synthesized […]

Methods for predicting cognitive decline in a subject

Alzheimer/u2019s disease is strongly linked to biological aging and bioenergetic abnormalities. Systemic dysregulation of metabolism is a hallmark of […]

Methods of determining whether a subject suffering from lupus

Systemic lupus erythematosus (SLE) is an autoimmune disease in which circulating immune complexes can cause different types of glomerulonephritis, […]

Methods and compositions for discriminating and treating stroke

Stroke is the second cause of death and the first cause of adult disability in industrialized countries. The goal of emergency therapy for acute […]

Stratificate and method to treat a patient suffering from a cancer

The present invention relates the stratification and treatment of patient suffering from a cancer. In this study, the inventors analyzed the adenosine […]