Methods for prognosis and monitoring pulmonaryhypertension

In the present invention, in Pulmonary Arterial Hypertension (PAH) patient/u2019s blood samples (EFFORT cohort), inventors results indicate that […]

Use of the population of slamf4+ ccr5+ effector memory cd4+ t cells as

CD4+ Foxp3- conventional T cells (Tconv) play a key role in the inflammatory process involved in rheumatoid arthritis (RA). It is now becoming […]

Method for determining the relative age of red blood cells

Glycated Hb was measured and compared between five healthy donors (AA), seven non-diabetic and non-transfused homozygous SCD patients (SS) and five […]

Cd81 as a biomarker and biotarget in t-cell malignancies

The present study of the regulatory T phenotype of Sézary cells led to the discovery of the overexpression of CD81 by Sézary cells. CD81 has also […]

Use of albumin isoforms profiles for the characterization of the

The inventors hypothesized that each type of liver injury can be revealed by a specific profile of HSA posttranslational modifications. Therefore, the […]

Methods and pharmaceutical compositions for the treatment of systemic

The present invention relates to methods and pharmaceutical compositions for the treatment of systemic mastocytosis. The inventors showed the effect […]

Lymphotoxin alpha regulates the immunosuppressive functions of

The present invention relates to regulatory T cell and uses thereof. By their immunosuppressive and anti-inflammatory activities, regulatory T cells […]

Methods for the diagnosis and treatment of t cell-lymphomas ccr8

T-cell lymphomas are a heterogeneous group of malignancies involving T lymphocytes and generally characterized by a poor prognosis. Among them, […]

Method for treating cancer

The present invention relates to a method of treating HER2EU overexpressing cancers. The inventors discovered that the heme-mediated formation of […]

Treatment of liver cancers by disrupting the beta-catenin/tcf-4

Activating mutations in CTNNB1 gene encoding β-catenin is encountered in approximately 30% of hepatocellular carcinoma (HCC) and in more than 80% of […]